Effect of Autologous Fat Grafting on Burn Scars: An Assessment using Patient and Observer Scar Assessment (POSAS) Scale
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Abstract
Context: Burns scars inversely affect the quality of life of the patients by affecting their physical, psychological, and social well-being. Autologous fat has adipose-derived stem cells with regenerative properties. Autologous fat grafting for the treatment of burns scars is a novel treatment modality that has not been studied adequately.
Aims: We have conducted this study to objectively assess the effect of autologous fat grafting on burns scars in terms of their aesthetic and functional outcomes at 6 weeks. We used the Patient and Observer Scar Assessment (POSAS) scale to record pre-procedure and post-procedure scores.
Settings and Design: Prospective non-randomized clinical study.
Methods and Material: Twenty-two (22) patients with 44 immature burn scars were treated with autologous fat by Coleman’s technique and assessed by POSAS scale preoperatively and 1,3,6 weeks, post-operatively. Statistical analysis was carried out and results were recorded.
Statistical Analysis: Data entry was done in Microsoft Excel and data analysis was done by SPSS software (version 20.0).
Results: The objective analysis by POSAS observer scale revealed a statistically significant improvement (p < 0.001) in vascularity, pigmentation, thickness, relief, pliability, and surface area at 6 weeks compared to its pre-operative status. The subjective analysis by POSAS patient scale revealed a statistically significant improvement (p < 0.001) in pain, itching, colour, stiffness, thickness, irregularity and the overall opinion of the patient and observer.
Conclusions: Autologous fat grafting was found to be a safe and effective treatment modality in the management of post-burn scars. An improvement in the aesthetic, as well as functional parameters like pain and itching, was noted.
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